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Inhibition of Vimentin or β1-integrin Reverts Morphology of Prostate Tumor Cells Grown in Laminin-rich ECM gels and Reduces Tumor Growth in vivo

Prostate epithelial cells grown embedded in laminin-rich extracellular matrix (lrECM) undergo morphological changes that closely resemble their architecture in vivo. In this study, growth characteristics of three human prostate epithelial sublines derived from the same cellular lineage, but displayi...

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Detalhes bibliográficos
Principais autores: Zhang, Xueping, Fournier, Marcia V., Ware, Joy L., Bissell, Mina J., Jacoub, Adly, Zehner, Zendra E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703491/
https://ncbi.nlm.nih.gov/pubmed/19276168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0544
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