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Chemoselective immobilization of biomolecules through aqueous Diels–Alder and PEG chemistry

Aqueous Diels–Alder chemistry combined with a poly(ethylene glycol) (PEG) spacer was used to immobilize a diverse group of biomolecules onto a solid surface. Briefly, α, ω linear PEG conjugates were synthesized containing cyclopentadiene in the α position and either biotin, lactose, or protein A in...

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Detalhes bibliográficos
Main Authors: Sun, Xue-Long, Yang, LiuChun, Chaikof, Elliot L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703444/
https://ncbi.nlm.nih.gov/pubmed/19568325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2008.02.111
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