Diversity-Generating Retroelement Homing Regenerates Target Sequences for Repeated Rounds of Codon Rewriting and Protein Diversification

Diversity-generating retroelements (DGRs) introduce vast amounts of sequence diversity into target genes. During mutagenic homing, adenine residues are converted to random nucleotides in a unidirectional, reverse transcriptase-dependent transposition process from a donor template repeat (TR) to a re...

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Bibliografiset tiedot
Päätekijät: Guo, Huatao, Tse, Longping V., Barbalat, Roman, Sivaamnuaiphorn, Sameer, Xu, Min, Doulatov, Sergei, Miller, Jeff F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703419/
https://ncbi.nlm.nih.gov/pubmed/18922465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.07.022
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