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Lymphotoxin-Mediated Crosstalk between B Cells and Splenic Stroma Promotes the Initial Type I Interferon Response to Cytomegalovirus
Toll-like receptor (TLR)-dependent pathways control the production of IFNαβ, a key cytokine in innate immune control of viruses including mouse cytomegalovirus (MCMV). The lymphotoxin (LT) αβ-LTβ receptor signaling pathway is also critical for defense against MCMV and thought to aid in the IFNβ resp...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2703178/ https://ncbi.nlm.nih.gov/pubmed/18312841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2007.12.008 |
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