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Reduced Viability, Fertility and Fecundity in Mice Lacking the Cajal Body Marker Protein, Coilin

BACKGROUND: Coilin is the signature protein of the Cajal body, a conserved nuclear organelle involved in multiple aspects of small ribonucleoprotein (RNP) biogenesis. Coilin is required for Cajal body homeostasis in both plants and animals. Mice lacking coilin are viable when the mutation is crossed...

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Main Authors: Walker, Michael P., Tian, Liping, Matera, A. Gregory
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702818/
https://ncbi.nlm.nih.gov/pubmed/19587784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006171
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