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NMR reveals hydrogen bonds between oxygen and distal histidines in oxyhemoglobin

Compared with free heme, the proteins hemoglobin (Hb) and myoglobin (Mb) exhibit greatly enhanced affinity for oxygen relative to carbon monoxide. This physiologically vital property has been attributed to either steric hindrance of CO or stabilization of O(2) binding by a hydrogen bond with the dis...

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Detalles Bibliográficos
Main Authors: Lukin, Jonathan A., Simplaceanu, Virgil, Zou, Ming, Ho, Nancy T., Ho, Chien
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC27028/
https://ncbi.nlm.nih.gov/pubmed/10962034
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