γ-Glutamyl transpeptidase is induced by 4-hydroxynonenal via EpRE/Nrf2 signaling in rat epithelial type II cells

γ-Glutamyl transpeptidase (GGT) plays key roles in glutathione homeostasis and metabolism of glutathione S-conjugates. Rat GGT is transcribed via five tandemly arranged promoters into seven transcripts. The transcription of mRNAV is controlled by promoter 5. Previously we found that GGT mRNAV-2 was...

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Main Authors: Zhang, Hongqiao, Liu, Honglei, Dickinson, Dale A., Liu, Rui-Ming, Postlethwait, Edward M., Laperche, Yannick, Forman, Henry Jay
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702664/
https://ncbi.nlm.nih.gov/pubmed/16631518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2005.11.005
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