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Variations in the NBN/NBS1 gene and the risk of breast cancer in non-BRCA1/2 French Canadian families with high risk of breast cancer

BACKGROUND: The Nijmegen Breakage Syndrome is a chromosomal instability disorder characterized by microcephaly, growth retardation, immunodeficiency, and increased frequency of cancers. Familial studies on relatives of these patients indicated that they also appear to be at increased risk of cancer....

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Autori principali: Desjardins, Sylvie, Beauparlant, Joly Charles, Labrie, Yvan, Ouellette, Geneviève, Durocher, Francine
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702391/
https://ncbi.nlm.nih.gov/pubmed/19523210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-181
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