Variations in the NBN/NBS1 gene and the risk of breast cancer in non-BRCA1/2 French Canadian families with high risk of breast cancer

BACKGROUND: The Nijmegen Breakage Syndrome is a chromosomal instability disorder characterized by microcephaly, growth retardation, immunodeficiency, and increased frequency of cancers. Familial studies on relatives of these patients indicated that they also appear to be at increased risk of cancer....

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Hauptverfasser: Desjardins, Sylvie, Beauparlant, Joly Charles, Labrie, Yvan, Ouellette, Geneviève, Durocher, Francine
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702391/
https://ncbi.nlm.nih.gov/pubmed/19523210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-181
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