Estimating the number needed to treat from continuous outcomes in randomised controlled trials: methodological challenges and worked example using data from the UK Back Pain Exercise and Manipulation (BEAM) trial

BACKGROUND: Reporting numbers needed to treat (NNT) improves interpretability of trial results. It is unusual that continuous outcomes are converted to numbers of individual responders to treatment (i.e., those who reach a particular threshold of change); and deteriorations prevented are only rarely...

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Main Authors: Froud, Robert, Eldridge, Sandra, Lall, Ranjit, Underwood, Martin
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2009
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702335/
https://ncbi.nlm.nih.gov/pubmed/19519911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2288-9-35
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