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Dantrolene: mechanisms of neuroprotection and possible clinical applications in the neurointensive care unit

BACKGROUND AND AIMS: Calcium plays a central role in neuronal function and injury. Dantrolene, an inhibitor of the ryanodine receptor, inhibits intracellular calcium release from the sarcoendoplasmic reticulum and might serve as novel agent for neuroprotection and other applications in the Neurointe...

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Main Authors: Muehlschlegel, Susanne, Sims, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702250/
https://ncbi.nlm.nih.gov/pubmed/18696266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12028-008-9133-4
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