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Heat-Induced Reactivation of HSV-1 in Latent Mice: Upregulation in the TG of CD83 and Other Immune Response Genes and Their LAT-ICP0 Locus

PURPOSE: To determine changes in host gene expression in HSV-1 latent trigeminal ganglia (TG) after hyperthermic stress. METHODS: Scarified corneas of 6-week-old female BALB/c mice were inoculated with either HSV-1 17Syn(+) (high phenotypic reactivator) or 17ΔPst(LAT(−)) (low phenotypic reactivator)...

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Detalhes bibliográficos
Main Authors: Clement, Christian, Bhattacharjee, Partha S., Kaufman, Herbert E., Hill, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702237/
https://ncbi.nlm.nih.gov/pubmed/19151393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-2430
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