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High serum IFN-α activity is a heritable risk factor for systemic lupus erythematosus

Interferon α (IFN-α) levels are elevated in many patients with systemic lupus erythematosus (SLE); however it is not known whether high serum IFN-α activity is a cause or a result of the disease. We studied 266 SLE patients and 405 of their healthy relatives, and frequently found high serum IFN-α ac...

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Detalhes bibliográficos
Main Authors: Niewold, TB, Hua, J, Lehman, TJA, Harley, JB, Crow, MK
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702174/
https://ncbi.nlm.nih.gov/pubmed/17581626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.gene.6364408
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