Soluble mediators from mesenchymal stem cells suppress T cell proliferation by inducing IL-10

Mesenchymal stem cells (MSCs) can inhibit T cell proliferation; however, the underlying mechanisms are not clear. In this study, we investigated the mechanisms of the immunoregulatory activity of MSCs on T cells. Irradiated MSCs co-cultured with either naïve or pre-activated T cells in a mixed lymph...

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Détails bibliographiques
Auteurs principaux: Yang, Seung-Ha, Park, Min-Jung, Yoon, Il-Hee, Kim, Su-Young, Hong, So-Hee, Shin, Jin-Young, Nam, Hye-Young, Kim, Yong-Hee, Kim, Bongi, Park, Chung-Gyu
Format: Artigo
Langue:Inglês
Publié: Korean Society of Medical Biochemistry and Molecular Biology 2009
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701980/
https://ncbi.nlm.nih.gov/pubmed/19307751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2009.41.5.035
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