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Staphylococcus aureus activates type I IFN signaling in mice and humans through the Xr repeated sequences of protein A

The activation of type I IFN signaling is a major component of host defense against viral infection, but it is not typically associated with immune responses to extracellular bacterial pathogens. Using mouse and human airway epithelial cells, we have demonstrated that Staphylococcus aureus activates...

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Bibliografische gegevens
Hoofdauteurs: Martin, Francis J., Gomez, Marisa I., Wetzel, Dawn M., Memmi, Guido, O’Seaghdha, Maghnus, Soong, Grace, Schindler, Christian, Prince, Alice
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701857/
https://ncbi.nlm.nih.gov/pubmed/19603548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35879
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