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Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice

Influenza-related complications continue to be a major cause of mortality worldwide. Due to unclear mechanisms, a substantial number of influenza-related deaths result from bacterial superinfections, particularly secondary pneumococcal pneumonia. Here, we report what we believe to be a novel mechani...

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Detalhes bibliográficos
Main Authors: Shahangian, Arash, Chow, Edward K., Tian, Xiaoli, Kang, Jason R., Ghaffari, Amir, Liu, Su Y., Belperio, John A., Cheng, Genhong, Deng, Jane C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701856/
https://ncbi.nlm.nih.gov/pubmed/19487810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35412
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