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Reactive oxygen species up-regulate CD11b in microglia via nitric oxide: Implications for neurodegenerative diseases

Microglial activation is considered as a hallmark of several neurodegenerative disorders. During microglial activation, the expression of CD11b, the beta-integrin marker of microglia, is increased. However, the molecular mechanism behind increased microglial CD11b expression is poorly understood. Th...

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Hlavní autoři: Roy, Avik, Jana, Arundhati, Yatish, Kavitha, Freidt, Matthew B., Fung, Yiu K., Martinson, Jeffrey A., Pahan, Kalipada
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701551/
https://ncbi.nlm.nih.gov/pubmed/18590811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.05.026
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