Llwytho...

In thrombin stimulated human platelets Citalopram, Promethazine, Risperidone, and Ziprasidone, but not Diazepam, may exert their pharmacological effects also through intercalation in membrane phospholipids in a receptor-independent manner

Intercalation of drugs in the platelet membrane affects phospholipid-requiring enzymatic processes according to the drugs’ intercalation capability. We investigated effects of Promethazine, Citalopram, Ziprasidone, Risperidone, and Diazepam on phospholipase A(2) (PLA(2)) and polyphosphoinositide (PP...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Oruch, Ramadhan, Hodneland, Erlend, Pryme, Ian F., Holmsen, Holm
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer-Verlag 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701490/
https://ncbi.nlm.nih.gov/pubmed/19568786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12154-009-0018-6
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