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Role of aliskiren in cardio-renal protection and use in hypertensives with multiple risk factors

The renin–angiotensin–aldosterone system (RAAS) is a key mediator of blood pressure (BP) and volume regulation in both normotensive and hypertensive persons. Stimulation of RAAS also contributes to hypertension-related target organ damage. The renin–angiotensinogen reaction is the first and rate-lim...

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Bibliographic Details
Main Authors: Pimenta, Eduardo, Oparil, Suzanne
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701487/
https://ncbi.nlm.nih.gov/pubmed/19707255
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