De Novo Induction of Genetically Engineered Brain Tumors In Mice Using Plasmid DNA

Spontaneous mouse models of cancer show promise to more accurately recapitulate human disease and predict clinical efficacy. Transgenic mice or viral vectors have been required to generate spontaneous models of glioma, a lethal brain tumor, because nonviral gene transfer is typically transient. To o...

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Auteurs principaux: Wiesner, Stephen M., Decker, Stacy A., Larson, Jon D., Ericson, Katya, Forster, Colleen, Gallardo, Jose L., Long, Chunmei, Demorest, Zachary L., Zamora, Edward A, Low, Walter C., SantaCruz, Karen, Largaespada, David A., Ohlfest, John R.
Format: Artigo
Langue:Inglês
Publié: 2009
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701484/
https://ncbi.nlm.nih.gov/pubmed/19147555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1800
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