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Identification of Undecaprenyl Phosphate-β-D-Galactosamine in Francisella novicida and Its Function in Lipid A Modification

Francisella tularensis is a highly infectious pathogen that causes tularemia. Francisella lipid A contains an unusual galactosamine (GalN) unit, attached to its 1-phosphate moiety. Two genes, flmF2 and flmK, are required for the addition of GalN to Francisella lipid A, but the relevant enzymes and t...

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Detalhes bibliográficos
Main Authors: Wang, Xiaoyuan, Ribeiro, Anthony A., Guan, Ziqiang, Raetz, Christian R. H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701470/
https://ncbi.nlm.nih.gov/pubmed/19166327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi802211k
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