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Cell-Specific Alterations of Glutamate Receptor Expression in Tuberous Sclerosis Complex Cortical Tubers

OBJECTIVE: Genetic loss of TSC1/TSC2 function in tuberous sclerosis complex (TSC) results in overactivation of the mammalian target of rapamycin complex 1 pathway, leading to cellular dysplasia. We hypothesized that the dysplastic cells in TSC tubers are heterogeneous, including separable classes on...

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Detalhes bibliográficos
Main Authors: Talos, Delia M., Kwiatkowski, David J., Cordero, Kathia, Black, Peter M., Jensen, Frances E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701384/
https://ncbi.nlm.nih.gov/pubmed/18350576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21342
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