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Decreased beta-adrenergic responsiveness following hypertrophy occurs only in cardiomyocytes that also re-express beta-myosin heavy chain

AIMS: Cardiac hypertrophy is associated with a reduction in the contractile response to beta-adrenergic stimulation, and with re-expression of foetal genes such as beta-myosin heavy chain (MHC). However, whether these two markers of pathology develop concordantly in the same individual cells or inde...

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Autori principali: Pandya, Kumar, Porter, Kristine, Rockman, Howard A., Smithies, Oliver
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701279/
https://ncbi.nlm.nih.gov/pubmed/19553396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurjhf/hfp073
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