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The Serotonin Transporter Gene and Disease Modification in Psychosis: Evidence for Systematic Differences in Allelic Directionality at the 5-HTTLPR Locus

A 44 base pair insertion (‘l”)/deletion (“s”) polymorphism (called 5-HTTLPR) in the 5′ promoter region of the human serotonin transporter gene (SLC6A4) modulates expression and has been associated to anxiety and depressive traits in otherwise healthy individuals. In individuals with psychiatric diag...

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Detalhes bibliográficos
Main Authors: Goldberg, Terry E., Kotov, Roman, Lee, Annette T., Gregersen, Peter K., Lencz, Todd, Bromet, Evelyn, Malhotra, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701255/
https://ncbi.nlm.nih.gov/pubmed/19361959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2009.03.021
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