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Enantioselective Total Synthesis of (-)-Pironetin: Iterative Aldol Reactions of Thiazolidinethiones

[Image: see text] The enantioselective total synthesis of pironetin has been achieved in 11 steps from known aldehyde 2. The synthesis relies on the formation of 5 out of 6 stereocenters through titanium mediated iterative aldol reactions. Key steps in this synthesis include an acetal aldol reaction...

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Detaylı Bibliyografya
Asıl Yazarlar: Crimmins, Michael T., Dechert, Anne-Marie R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701212/
https://ncbi.nlm.nih.gov/pubmed/19281219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol9003228
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