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Distinct spatial activation of intrinsic and extrinsic apoptosis pathways in natural scrapie: association with prion-related lesions

Neurodegeneration and gliosis are the main neuropathological features of prion diseases. However, the molecular mechanisms involved in these processes remain unclear. Several studies have demonstrated changes in the expression of apoptotic factors and inflammatory cytokines in animals with experimen...

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Bibliografiske detaljer
Main Authors: Serrano, Carmen, Lyahyai, Jaber, Bolea, Rosa, Varona, Luis, Monleón, Eva, Badiola, Juan J., Zaragoza, Pilar, Martín-Burriel, Inmaculada
Format: Artigo
Sprog:Inglês
Udgivet: EDP Sciences 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701179/
https://ncbi.nlm.nih.gov/pubmed/19401142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1051/vetres/2009024
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