Requirement for AHNAK1-mediated calcium signaling during T lymphocyte cytolysis

Cytolytic CD8(+) T cells (CTLs) kill virally infected cells, tumor cells, or other potentially autoreactive T cells in a calcium-dependent manner. To date, the molecular mechanism that leads to calcium intake during CTL differentiation and function has remained unresolved. We demonstrate that desmoy...

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Bibliografiske detaljer
Main Authors: Matza, Didi, Badou, Abdallah, Jha, Mithilesh K., Willinger, Tim, Antov, Andrey, Sanjabi, Shomyseh, Kobayashi, Koichi S., Marchesi, Vincent T., Flavell, Richard A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701053/
https://ncbi.nlm.nih.gov/pubmed/19497879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902844106
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