Optimal neuroprotection by erythropoietin requires elevated expression of its receptor in neurons

Erythropoietin receptor (EpoR) binding mediates neuroprotection by endogenous Epo or by exogenous recombinant human (rh)Epo. The level of EpoR gene expression may determine tissue responsiveness to Epo. Thus, harnessing the neuroprotective power of Epo requires an understanding of the Epo–EpoR syste...

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Detalhes bibliográficos
Main Authors: Sanchez, Pascal E., Fares, Raafat P., Risso, Jean-Jacques, Bonnet, Chantal, Bouvard, Sandrine, Le-Cavorsin, Marion, Georges, Béatrice, Moulin, Colette, Belmeguenai, Amor, Bodennec, Jacques, Morales, Anne, Pequignot, Jean-Marc, Baulieu, Etienne-Emile, Levine, Robert A., Bezin, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701030/
https://ncbi.nlm.nih.gov/pubmed/19497871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901840106
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