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Scaffold expulsion and genome packaging trigger stabilization of herpes simplex virus capsids

Herpes simplex virus type 1 (HSV1) capsids undergo extensive structural changes during maturation and DNA packaging. As a result, they become more stable and competent for nuclear egress. To further elucidate this stabilization process, we used biochemical and nanoindentation approaches to analyze t...

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Detalhes bibliográficos
Main Authors: Roos, Wouter H., Radtke, Kerstin, Kniesmeijer, Edward, Geertsema, Hylkje, Sodeik, Beate, Wuite, Gijs J. L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700990/
https://ncbi.nlm.nih.gov/pubmed/19487681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901514106
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