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The cytokine interleukin-33 mediates anaphylactic shock

Anaphylactic shock is characterized by elevated immunoglobulin-E (IgE) antibodies that signal via the high affinity Fcε receptor (FcεRI) to release inflammatory mediators. Here we report that the novel cytokine interleukin-33 (IL-33) potently induces anaphylactic shock in mice and is associated with...

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Detalhes bibliográficos
Main Authors: Pushparaj, Peter N., Tay, Hwee Kee, H'ng, Shiau Chen, Pitman, Nick, Xu, Damo, McKenzie, Andrew, Liew, Foo Y., Melendez, Alirio J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700978/
https://ncbi.nlm.nih.gov/pubmed/19506243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901206106
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