Structure-Function Analysis of Nucleolin and ErbB Receptors Interactions

BACKGROUND: The ErbB receptor tyrosine kinases and nucleolin are major contributors to malignant transformation. Recently we have found that cell-surface ErbB receptors interact with nucleolin via their cytoplasmic tail. Overexpression of ErbB1 and nucleolin leads to receptor phosphorylation, dimeri...

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Bibliographic Details
Main Authors: Farin, Keren, Di Segni, Ayelet, Mor, Adam, Pinkas-Kramarski, Ronit
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700965/
https://ncbi.nlm.nih.gov/pubmed/19578540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006128
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