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Explicitly Representing the Solvation Shell in Continuum Solvent Calculations

A method is presented to explicitly represent the first solvation shell in continuum solvation calculations. Initial solvation shell geometries were generated with classical molecular dynamics simulations. Clusters consisting of solute and 5 solvent molecules were fully relaxed in quantum mechanical...

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Autors principals: da Silva, Eirik F., Svendsen, Hallvard F., Merz, Kenneth M.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700946/
https://ncbi.nlm.nih.gov/pubmed/19425558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp809712y
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