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Haplotype associations with quantitative traits in the presence of complex multilocus and heterogeneous effects

In genetic mapping of complex traits, scored haplotypes are likely to represent only a subset of all causal polymorphisms. At the extreme of this scenario, observed polymorphisms are not themselves functional, and only linked to causal ones via linkage disequilibrium (LD). We will demonstrate that d...

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Bibliografiske detaljer
Main Authors: Shibata, Kyoko, Diatchenko, Luda, Zaykin, Dmitri V.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700858/
https://ncbi.nlm.nih.gov/pubmed/18636529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20358
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