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γ-Aminobutyric acid type B receptors are expressed and functional in mammalian cardiomyocytes

γ-Hydroxybutyrate (GHB), an anesthetic adjuvant analog of γ-aminobutyrate (GABA), depresses cell excitability in hippocampal neurons by inducing hyperpolarization through the activation of a prominent inwardly rectifying K(+) (Kir3) conductance. These GABA type B (GABA(B))-like effects are clearly s...

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Detalhes bibliográficos
Main Authors: Lorente, Paco, Lacampagne, Alain, Pouzeratte, Yvan, Richards, Stephen, Malitschek, Barbara, Kuhn, Rainer, Bettler, Bernhard, Vassort, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC27005/
https://ncbi.nlm.nih.gov/pubmed/10900022
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