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Cdc28/Cdk1 positively and negatively affects genome stability in S. cerevisiae
We studied the function of the cyclin-dependent kinase Cdc28 (Cdk1) in the DNA damage response and maintenance of genome stability using Saccharomyces cerevisiae. Reduced Cdc28 activity sensitizes cells to chronic DNA damage, but Cdc28 is not required for cell viability upon acute exposure to DNA-da...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2700387/ https://ncbi.nlm.nih.gov/pubmed/19398760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200811083 |
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