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Estrogen attenuates glutamate-induced cell death by inhibiting Ca(2+) influx through L-type voltage-gated Ca(2+) channels

Estrogen-mediated neuroprotection is observed in neurodegenerative disease and neurotrauama models; however, determining a mechanism for these effects has been difficult. We propose that estrogen may limit cell death in the nervous system tissue by inhibiting increases in intracellular free Ca(2+)....

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Detalhes bibliográficos
Main Authors: Sribnick, Eric A., Del Re, Angelo M., Ray, Swapan K., Woodward, John J., Banik, Naren L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700344/
https://ncbi.nlm.nih.gov/pubmed/19389388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.04.022
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