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Tumor suppressor microRNAs are underrepresented in primary effusion lymphoma and Kaposi sarcoma

The presence of tumor-specific microRNAs reflects tissue of origin and tumor stage. We show that the absence of miRNAs likewise can be used to determine tumor origin (miR-155) and proliferation state because tumor suppressor miRNAs (miR-222/221, let-7 family) were significantly down-regulated in pri...

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Bibliografiske detaljer
Main Authors: O'Hara, Andrea J., Wang, Ling, Dezube, Bruce J., Harrington, William J., Damania, Blossom, Dittmer, Dirk P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700328/
https://ncbi.nlm.nih.gov/pubmed/19252139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-09-179168
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