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Acquisition of Cell–Cell Fusion Activity by Amino Acid Substitutions in Spike Protein Determines the Infectivity of a Coronavirus in Cultured Cells

Coronavirus host and cell specificities are determined by specific interactions between the viral spike (S) protein and host cell receptor(s). Avian coronavirus infectious bronchitis (IBV) has been adapted to embryonated chicken eggs, primary chicken kidney (CK) cells, monkey kidney cell line Vero,...

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Detalhes bibliográficos
Main Authors: Yamada, Yoshiyuki, Liu, Xiao Bo, Fang, Shou Guo, Tay, Felicia P. L., Liu, Ding Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700284/
https://ncbi.nlm.nih.gov/pubmed/19572016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006130
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