Excess “read-through” acetylcholinesterase attenuates but the “synaptic” variant intensifies neurodeterioration correlates

Acute stress increases the risk for neurodegeneration, but the molecular signals regulating the shift from transient stress responses to progressive disease are not yet known. The “read-through” variant of acetylcholinesterase (AChE-R) accumulates in the mammalian brain under acute stress. Therefore...

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Detalhes bibliográficos
Main Authors: Sternfeld, Meira, Shoham, Shai, Klein, Omer, Flores-Flores, Cesar, Evron, Tamah, Idelson, Gregory H., Kitsberg, Dani, Patrick, James W., Soreq, Hermona
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC27002/
https://ncbi.nlm.nih.gov/pubmed/10890884
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