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Restoration of Calcium Influx Corrects Membrane Hyperexcitability in Injured Rat Dorsal Root Ganglion Neurons

We have previously shown that a decrease of inward Ca(2+) flux (I(Ca)) across the sensory neuron plasmalemma, such as happens after axotomy, elevates neuronal excitability. From this, we predicted that increasing I(Ca) in injured neurons should correct their hyperexcitability, which we have tested d...

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Détails bibliographiques
Auteurs principaux: Hogan, Quinn, Lirk, Philipp, Poroli, Mark, Rigaud, Marcel, Fuchs, Andreas, Fillip, Patrick, Ljubkovic, Marko, Sapunar, Damir
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700057/
https://ncbi.nlm.nih.gov/pubmed/18713927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ane.0b013e31817bd1f0
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