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Effects of 1,4-phenylenebis(methylene)selenocyanate on mutagenesis and p53 protein expression in the tongue of lacI rats treated with 4-nitroquinoline-N-oxide
Previously we showed that the organoselenium compound, 1,4-phenylenebis(methylene)selenocyanate (p-XSC) inhibits 4-nitroquinoline-N-oxide (4-NQO)-induced tongue tumorigenesis in Fisher rats. Here we investigate possible mechanisms of this inhibition by monitoring mutagenesis and p53 protein levels i...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2700054/ https://ncbi.nlm.nih.gov/pubmed/17720616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrgentox.2007.07.005 |
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