A novel method for oral delivery of drug compounds to the neonatal SMNΔ7 mouse model of spinal muscular atrophy

Spinal muscular atrophy (SMA) is a devastating motor neuron disease that is one of the leading genetic causes of infant mortality. Currently, there is no cure for SMA. Mouse models that genetically and phenotypically resemble SMA have been generated and have the potential to be used for the discover...

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Bibliographic Details
Main Authors: Butchbach, Matthew E. R., Edwards, Jonathan D., Schussler, Kristie R., Burghes, Arthur H. M.
Format: Artigo
Language:Inglês
Published: 2006
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699996/
https://ncbi.nlm.nih.gov/pubmed/17161463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2006.11.002
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