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Incorporating sequence information into the scoring function: a hidden Markov model for improved peptide identification

MOTIVATION: The identification of peptides by tandem mass spectrometry (MS/MS) is a central method of proteomics research, but due to the complexity of MS/MS data and the large databases searched, the accuracy of peptide identification algorithms remains limited. To improve the accuracy of identific...

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Detalhes bibliográficos
Main Authors: Khatun, Jainab, Hamlett, Eric, Giddings, Morgan C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699941/
https://ncbi.nlm.nih.gov/pubmed/18187442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btn011
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