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Stereoselective Synthesis of 2-Deoxy-β-Glycosides Using Anomeric O-Alkylation/Arylation

[Image: see text] Anomeric O-alkylation/arylation is applied to the synthesis of 2-deoxy-β-glycosides. Treatment of lactols with NaH in dioxane followed by the addition of electrophiles leads to the formation of 2-deoxy-β-glycosides in high yield and high selectivity. The high β-selectivity observed...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Morris, William J., Shair, Matthew D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699938/
https://ncbi.nlm.nih.gov/pubmed/19061365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol8022006
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