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Nippostrongylus brasiliensis: Identification of Intelectin-1 and -2 as Stat6-dependent genes expressed in lung and intestine during infection

Elimination of the helminth parasite Nippostrongylus brasiliensis from infected mice is mediated by IL-4 or IL-13 and dependent on the IL-4Rα chain and the transcription factor Stat6 in non-hematopoietic cells. However, it is not clear which Stat6-dependent effector molecules mediate worm expulsion....

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Detalhes bibliográficos
Main Authors: Voehringer, David, Stanley, Sarah A., Cox, Jeffery S., Completo, Gladys C., Lowary, Todd L., Locksley, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699772/
https://ncbi.nlm.nih.gov/pubmed/17420014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exppara.2007.02.015
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