A crescent shaped ALIX dimer targets ESCRT-III CHMP4 filaments

ALIX recruits ESCRT-III CHMP4 and is involved in membrane remodeling during endosomal receptor sorting, budding of some enveloped viruses and cytokinesis. We show that ALIX dimerizes via the middle domain (ALIX(-V)) in solution. Structural modeling based on small angle X-ray scattering (SAXS) data r...

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Main Authors: Pires, R., Hartlieb, B., Signor, L., Schoehn, G., Lata, S., Roessle, M., Moriscot, C., Popov, S., Hinz, A., Jamin, M., Boyer, V., Sadoul, R., Forest, E., Svergun, D. I., Göttlinger, H. G., Weissenhorn, W.
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699623/
https://ncbi.nlm.nih.gov/pubmed/19523902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.04.007
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