Transcriptionally active PCR for antigen identification and vaccine development: in vitro genome-wide screening and in vivo immunogenicity

We have evaluated a technology called Transcriptionally Active PCR (TAP) for high throughput identification and prioritization of novel target antigens from genomic sequence data using the Plasmodium parasite, the causative agent of malaria, as a model. First, we adapted the TAP technology for the h...

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Detalhes bibliográficos
Main Authors: Regis, David P., Dobaño, Carlota, Quiñones-Olson, Paola, Liang, Xiaowu, Graber, Norma L., Stefaniak, Maureen E., Campo, Joseph J., Carucci, Daniel J., Roth, David A., He, Huaping, Felgner, Philip L., Doolan, Denise L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699467/
https://ncbi.nlm.nih.gov/pubmed/18164079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2007.11.009
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