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Computational Challenges in miRNA Target Predictions: To Be or Not to Be a True Target?

All microRNA (miRNA) target—finder algorithms return lists of candidate target genes. How valid is that output in a biological setting? Transcriptome analysis has proven to be a useful approach to determine mRNA targets. Time course mRNA microarray experiments may reliably identify downregulated gen...

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Bibliografische gegevens
Hoofdauteurs: Barbato, Christian, Arisi, Ivan, Frizzo, Marcos E., Brandi, Rossella, Da Sacco, Letizia, Masotti, Andrea
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi Publishing Corporation 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699446/
https://ncbi.nlm.nih.gov/pubmed/19551154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/803069
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