DC activated via dectin-1 convert Treg into IL-17 producers

Th cells producing IL-17 play a pro-inflammatory role at mucosal surfaces. Treg at the same sites dampen inflammation and prevent immunopathology. Th cells producing IL-17 (Th17) and Treg are thought to be distinct populations defined by expression of the transcription factors ROR-γt and Foxp3, resp...

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Bibliografiska uppgifter
Huvudupphovsmän: Osorio, Fabiola, LeibundGut-Landmann, Salomé, Lochner, Matthias, Lahl, Katharina, Sparwasser, Tim, Eberl, Gérard, Reis e Sousa, Caetano
Materialtyp: Artigo
Språk:Inglês
Publicerad: WILEY-VCH Verlag 2008
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699423/
https://ncbi.nlm.nih.gov/pubmed/19039774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838950
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