TAK1 is an essential regulator of BMP signalling in cartilage

TGFβ activated kinase 1 (TAK1), a member of the MAPKKK family, controls diverse functions ranging from innate and adaptive immune system activation to vascular development and apoptosis. To analyse the in vivo function of TAK1 in cartilage, we generated mice with a conditional deletion of Tak1 drive...

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Detalhes bibliográficos
Main Authors: Shim, Jae-Hyuck, Greenblatt, Matthew B, Xie, Min, Schneider, Michael D, Zou, Weiguo, Zhai, Bo, Gygi, Steven, Glimcher, Laurie H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699391/
https://ncbi.nlm.nih.gov/pubmed/19536134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.162
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