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Nucleotide recognition by CopA, a Cu(+)-transporting P-type ATPase

Heavy metal pumps constitute a large subgroup in P-type ion-transporting ATPases. One of the outstanding features is that the nucleotide binding N-domain lacks residues critical for ATP binding in other well-studied P-type ATPases. Instead, they possess an HP-motif and a Gly-rich sequence in the N-d...

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Bibliographic Details
Main Authors: Tsuda, Takeo, Toyoshima, Chikashi
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699366/
https://ncbi.nlm.nih.gov/pubmed/19478797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.143
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